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International Business Times: AI meets enzymes - eXoZymes enables high-yield production of compounds previously impossible to make

Written by eXoZymes | Dec 17, 2025 2:27:09 PM

Article excerpt

Chemical compounds with high therapeutic value often come with an impossible catch: they exist in tiny amounts in rare plants, fungi, or other natural sources. Extracting them can take tons of raw material, leaving environmental scars, or require toxic petrochemical processes that produce hazardous waste. For decades, scientists tried to overcome these limits by using synthetic biology: engineering living cells to produce molecules, but scaling these methods from lab to factory remained a near-impossible challenge. Yields were low, cells resisted foreign tasks, and production often failed to reach commercial levels. A new class of technology is emerging to tackle this challenge: exozymes.

Michael Heltzen, CEO of eXoZymes, describes the breakthrough simply: "Cells weren't built to manufacture what we need, and they fight us every step of the way as they only want to make chemicals they themselves benefit from and only at the amount they need it. Using AI-enhanced eXoZymes, we flip the model, as there are no living cells in our biosolutions."

Full article available here

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